[유기화학실험] Triphenylmethanol from Benzophenone & Completion of Grignard Reaction(영문)

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[유기화학실험] Triphenylmethanol from Benzophenone & Completion of Grignard Reaction(영문)에 대한 자료입니다.
목차
-BackGround
-Chemicals
1. Phenylmagnesium Bromide (in ether)
2. Benzophenone
3. Triphenylmethanol
-Procedure
본문내용
BackGround

 Victor Grignard designed a carbon-carbon bond-forming reaction from appropriate alkyl halides and carbonyl compounds without producing alcohol. The Grignard reagent is easily formed by reaction of an alkyl halide, in particular a bromide, with magnesium metal in anhydrous diethyl ether. Although the reaction can be written and thought of as simply


 It appears that the structure of the material in solution is rather more complex. There is evidence that dialkylmagnesium is present.

  The Grignard reagent is both a strong base and a strong nucleophile. As a base it will react with all protons that are more acidic than those found on alkenes and alkanes. Thus, Grignard reagents react readily with water, alcohols, amines, thiols, and so on, to regenerate the alkane :