[논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells

 1  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-1
 2  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-2
 3  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-3
 4  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-4
 5  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-5
 6  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-6
 7  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-7
 8  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-8
 9  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-9
 10  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-10
 11  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-11
 12  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-12
 13  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-13
 14  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-14
 15  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-15
 16  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-16
 17  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-17
 18  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-18
 19  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-19
 20  [논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells-20
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  • 논문 > 자연계열
  • 2010.05.30
  • 32페이지 / ppt
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[논문발표PPT] RhoA –and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells에 대한 자료입니다.
본문내용
We have shown that in colonic smooth muscle, PKC-α and RhoA translocate and associate with each other in the particulate fraction in response to stimulation with acetylcholine.

We have also shown that RhoA interacts directly with PKC-α in vitro.


1) In human endothelial cells, activation of ROCK by RhoA requires PKC activation .
(1998,Hippenstiel S et al)

2) We have recently shown that preincubation of SMCs with Y-27632(specific ROCKII inhibitor), partially inhibited contraction(~50%) concomitant with inhibition of association of ROCKII with HSP27 in the particulate fraction .(2004,Patil SB, et al)

The aims of the studies were to investigate
the agonist-induced possible association and
translocation of MYPT with HSP27 and to
examine the roles played by RhoA and PKC
pathways in the regulation of MLCP activity.


참고문헌
Am J Physiol Gastrointest Liver Physial Vol. 290, No.G83-G95, 2006
(Suresh B. Patil and Khalil N. Bitar)
하고 싶은 말
대학원 석사과정 때 위 논문을 읽고 발표한 PPT입니다.
PPT에 발표 스크립트도 포함되어 있습니다.
논문읽고 발표수업 하실 때 참고하시면 많은 도움 되실겁니다.
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