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분야
ppt2.Cosmeceutical vehicle types
3.Preservatives and chelating agents
4.Anionics
5.Nonionic surfactants
6.Esters
7.Colorants in cosmetic products
8.Sourcing of ingredients
9.Solvents & diluents
10.Exceptions to labeling
11.Formulation of cosmeceutical vehicles
Alkanolamides are named by the specific alkyl amide stem & appropriate abbreviation.
Ethoxylated alcohols will have the alcoholic stem name with “-eth”
Straight-chain alkyl groups uaually contain the prefix “-iso”
Biologic materials are named when the materials has been isolated, purified, and chemically identified.
Minerals are named according to the nomenclature established in published mineralogy texts.
Formulation of cosmeceutical vehicles
A properly formulated vehicle is critical to deliver the cosmeceutical active to the skin most effectively.
1 Oily emollients can help reduce friction between skin surfaces & between skin & clothing.
2-1Water from o/w emulsions can help to swell the SC, increasing the ability of actives to penetrate skin.
2-2 IN w/o emulsions, water is slowly released & reaches the upper layers of skin .
Enhanced hydrated skin can result in an additional twofold to threefold increase in the rate of absorption to water & other polar molecules in skin.
3. Occlusive vehicles :
①Suppress transepidermal water loss.
② Increase absorption of actives.
Other factors effect penetration of active.
⇒Table 14.
4-1. An active with an acidic pH should be formulated with a pH that is acidic to neutral.
4-2. Actives with a basic pH should be formulated in vehicles that are neutral to slightly basic.
