[병리학] 바이러스성 수막염
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분야
docx-HSV2
-Varicella zoster virus (VZV)
-Mumps virus
-Symptoms of herpes simplex virus infection include watery blisters in the skin or mucou membranes of the mouth, lips or genitals.
-as neurotropic and neuroinvasive viruses, HSV-1 and -2 persist in the body for the life of the carrier by becoming latent and hiding from the immune system in the cell bodies of nerves.
-After the initial or primary infection, some infected people experience sporadic episodes of viral reactivation or outbreaks.
-Inclusion body: Tzanck cell
Varicella zoster virus (VZV)
-one of eight herpes viruses known to infect humans (and other vertebrates).
-It commonly causes chicken-pox in children and both shingles and postherpetic neuralgia in adults and rarely in children.
-Primary VZV infection results in chickenpox (varicella), which may rarely result in complications including meningoencephalitis or pneumonia.
-Even when clinical symptoms of chickenpox have resolved, VZV remains dormant in the nervous system of the infected person (virus latency), in the trigeminal and dorsal root ganglia.]
-In about 10-20% of cases, VZV reactivates later in life producing a disease known as herpes zoster or shingles. Serious complications of shingles include postherpetic neuralgia, zoster multiplex, myelitis, herpes ophthalmicus, or zoster sine herpete.
