소개글
[의약유전학] 유전학 관련 노벨상 5개 조사(영문)에 대한 자료입니다.
목차
1.The Chromosomal Theory of Heredity
2.the molecular basis of eukaryotic transcription
3.RNA interference
4.Knockout Mice
5.Telomeres
본문내용
To make breakthrough progress in the molecular understanding of transcription and its regulation
disturbances in transcriptional regulation contribute cancer, inflammation, heart disease and metabolic diseases.
Essential to be able to direct this development to form only the wanted type of cells
Gene targeting in ES cell
1. ES cell culture
2. Construction of targeting vector
3. ES cell transfection
4. Proliferation of targeted ES cell
From gene targeted ES cells to
gene targeted mice
5. Injection of ES cells into blastocysts
6. Birth and breeding of mosaic mice