Concepts of science have been developed by occupying ``ecological niche`` within conceptual ecology. The ecological niche is determined from the mutual effect between intellectual environmental of the learner and new concept, which few studies have been conducted. This study examined how the ecological niche of the concept of photosynthesis in 7th grade is changed by instruction. The ecological niche was analyzed using 2 methods: (1) the change in the diversity of concepts, and (2) the change in the proximity of concepts based on the frequency and the relativeness score of the concepts. The concept of photosynthesis was analyzed in the 4 domains in the place of photosynthesis, products of photosynthesis, reactants of photosynthesis, and environmental factors. The results of this study are as follows: (1) reduced diversity of concepts, (2) increased frequency and relativeness score of the scientific concepts, and (3) increased proximity of the scientific concepts by instruction. With these results, the mutual effects of the concepts within the conceptual ecology have become active by class to differentiate the relationships between the concepts, which accordingly displayed their changes in status.