원저 : 다양한 조직학적 소견을 보이는 간의 혈관근지방종: 간세포암종 혹은 염증성 거짓종양과 유사한 8예
분야
의약학 > 내과학
저자
황일선 ( Ii Seon Hwang ) , 유은실 ( Eun Sil Yu ) , 조경자 ( Kyung Ja Cho )
발행기관
대한소화기학회
간행물정보
대한소화기학회지 2012년, 제60권 제4호, 242~248페이지(총7페이지)
파일형식
07811270.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Background/Aims: Hepatic angiomyolipoma (AML) is a rare mesenchymal tumor of the liver and demonstrates a marked histologic diversity. HMB-45 is a promising immunomarker for this tumor and especially helpful to diagnosis of some AMLs with unusual morphology. The purpose of this study was to better define the variable histologic feature of hepatic AML. Methods: Eight hepatic AMLs were examined, and all of that were resection specimens. The diagnosis was confirmed by the presence of HMB-45 positive cells. Median age was 41.5 years old, and mean size of tumor was 8.94 cm. Results: Conventional mixed type was 5 cases which showed myomatous, angiomatous and lipomatous component, and 3 cases were myomatous predominant. Variable patterns including spider web cell morphology, solid sheet-like and trabecular pattern were identified on myomatous component and variable amount and patterns of inflammatory cell infiltration was identified. Conclusions: With only histologic features, it is difficult to distinguish hepatic AML from other hepatic tumor including hepatocellular carcinoma or inflammatory pseudotumor. A correct diagnosis of hepatic AML is possible by a close histologic examination with immunohistochemical stainings such as HMB-45 which is important to patient`s prognosis.
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