Predictable factors of histologic discrepancy of gastric tumor between the endoscopic forceps biopsy and endoscopic treatment specimen
분야
의약학 > 내과학
저자
( Ji Ho Kim ) , ( Sung Hoon Kim ) , ( Won Hyeong Park ) , ( Ji Sun Jang ) , ( Jei So Bang ) , ( Soo Hyun Yang ) , ( Jong Hoon Byun ) , ( Yoon Jung Kim )
발행기관
대한내과학회
간행물정보
대한내과학회 추계학술발표논문집 2011년, 제2011권 제1호, 50(총1쪽)
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    영문초록
    Purpose: Recently, variable gastrointestinal tract tumors including early stage malignancies are treated by endoscopic procedure. But, sometimes the discrepancies of histologic diagnosis happened between the pretreatment results and post-treatment results, especially in the aspect of malignancy. So, we retrospectively reviewed the patients who were not diagnosed as malignancy by forcep biopsy and were treated by EMR or ESD. Then, we investigated the predictable factors of histologic discrepancy between forcep biopsied and endoscopically resected specimen in terms of malignancy by comparing the clinical and endoscopic features through the lesions which were diagnosed as adenoma in forceps biopsy but diagnosed as adenocarcinoma in endoscopically resected specimen. Methods: From March 2008 to April 2011, 129 gastric tumor lesions (119 patients) which were not diagnosed as malignancy and were treated with endoscopic procedure were enrolled retrospectively. We compared the pretreatment endoscopic forceps biopsy results and post-treatment specimen biopsy results, then, analyzed the tumor characteristics. Results: When we compared the biopsy results, histologic discrepancies happened in 21 cases (16.3%) in terms of malignancy. Especially, these situations occurred more frequently in depressed lesions than in the flat or elevated lesions (41.7% vs 13.7%, p=0.012), and in the lesions diagnosed as high grade adenomas than in those diagnosed as low or moderate grade adenomas (33.3% vs. 11.1%, p=0.004). Conclusions: Overall, 16.3% of meaningful histologic discrepancies happened in terms of malignancy between the forceps biopsy and post endoscopic procedure specimen, and those occurred frequently in depressed type lesion and those diagnosed as high grade adenoma significantly.
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