Synchronous hepatocellular carcinoma and cholangiocarcinoma which were incidentally found and successfully treated by liver transplantation
의약학 > 내과학
임선영 , 김지훈
대한내과학회 추계학술발표논문집 2011년, 제2011권 제1호, 107(총1쪽)
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    Synchronous hepatocellular carcinoma (HCC) and cholangiocellular carcinoma (CCC) is type A carcinoma according Allen and Lisa classification which originate from different cell sites but consisting of a uniform cell type (double cancer or separate types). There is only a limited information regarding clinical features, pathologic features, survival outcomes, and prognostic factors due to the rarity of this double primary cancer. Most of the synchronous HCC and CCC patients have underlying liver cirrhosis as a cause of either viral hepatitis B or C and uncommonly alcohol. Synchronous HCC and CCC is difficult to diagnose based on the image studies only and mostly were diagnosed incidentally after resection. We herein report a case of 51-year-old male patient who was referred for the evaluation of the hepatic mass and ascites. The patient was a chronic alcoholic with negative viral marker. Initially multiple HCCs was diagnosed according to the dynamic liver CT and dynamic MRI and the patient was treated with liver transplantation but histopathologic findings revealed synchronous HCC and CCC. To our knowledge, only one brief case report of alcoholic liver cirrhosis with HCC finally diagnosed as synchronous HCC and CCC after liver transplant had been reported. Therefore this is the first case report of synchronous HCC and CCC which were incidentally found and successfully treated by liver transplanation with image studies and histopathologic findings in more detail.
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