Difference in Clinical Characteristics of Ischemic Heart Failure in Korean Patients with Acute Myocardial Infarction
의약학 > 내과학
( Min Suk Kim ) , ( Myung Ho Jeong ) , ( Sung Soo Kim ) , ( Min Goo Lee ) , ( Keun Ho Park ) , ( Doo Sun Sim ) , ( Nam Sik Yoon ) , ( Hyun Ju Yoon ) , ( Young Joon Hong ) , ( Ju Han Kim ) , ( Young Keun Ahn ) , ( Jeong Gwan Cho ) , ( Jong Chun Park ) , (
대한내과학회 추계학술발표논문집 2011년, 제2011권 제1호, 164(총1쪽)
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    Background: The purpose of this study is to define the differences of predictors of ischemic heart failure (IHF) in Korean patients with acute myocardial infarction (MI). Methods: Clinical characteristics analysis was performed in total 11,581 patients from the Korea Acute Myocardial Infarction Registry, who were divided into two groups according to the initial left ventricular ejection fraction (LVEF): goup 1 (LVEF<40%, N=2271) and group 2 (LVEF≥40%, N=9310). Differences in clinical characteristics were compared between the groups and 1-year major adverse cardiac events (MACE) were analyzed in group 1. Results: Average LVEF were 33.0±6.4% in group 1 and 55.9±14.1% in group 2. Group 1 showed higher prevalence of male (p=0.02), Killip class>III (p=0.034), previous history of angina pectoris (p=0.001), hypertension (p=0.034), diabetes mellitus (p=0.027), smoking (p=0.045), age>65 years (p=0.015), systolic blood pressure<80 mmHg (p=0.033), heart rate>100 beats/min (p=0.027), elevated creatine, elevated cardiac markers (creatine kinase, CK-MB, troponin-I) (p=0.001), elevated total cholesterol (p=0.031), elevated triglyceride (p=0.022), and cardiac arrest on arrival (p=0.001). The predictors of 1-year MACE in group 1 were high N-terminal pro-B-type natriuretic peptide (NT pro-BNP) (p=0.001), multivessel disease(p=0.001), cardiogenic shock (p=0.02), and elevated creatine (p=0.024). Conclusion: Korean patients with acute MI and initial IHF were older; more likely to have multiple risk factors and comorbidities including cardiogenic shock and cardiac arrest on arrival. The predictors of 1-year MACE in patients with IHF were high NT pro-BNP, multivessel disease, cardiogenic shock, and acute kidney injury. Acute Myocardial Infarction Registry Investigators.
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