Increased prevalence of cerebral infarction in patients with atopic dermatitis and low economic status: DATA from KNHANES IV
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Introduction: The Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) data revealed high prevalence of end organ damage in Korean hypertensive population. We aimed to identify predictors for cerebral infarction in patients with hypertension from nationwide registry data. Methods: We analyzed 1,564 patients (male 44.8%, Age 63.6±12.1yrs) with diagnosed hypertension from KNHANES IV. We checked baseline demographic data and various clinical risk factors for cerebrovascular disease. Cross sectional analysis was performed to indentify predictors of cerebral infarction in selected patient cohort. Results: Diagnosis of cerebral infarction was confirmed in 102 patients (6.5%). In univariate analysis, old age, lower economic status, presence of hyperlipidemia, major depression, atopic dermatitis and proteinuria had statistically significant correlation with cerebral infarction. After multivariate analysis, low economic status (p=0.001, HR=3.088), atopic dermatitis(p=0.015, HR=3.294) and old age (0=0.001, HR=1.035) remained independent predictors of cerebral infarction. Conclusion: In addition to classical risk factors for cerebral infarction, presence of atopic dermatitis and low economic status were independent risk factors of cerebral infarction in Korean hypertensive population.
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