Primary Malignant Melanoma of the Lung - Imaging characteristics of malignant melanoma in lung
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Melanoma is a cutaneous malignant neoplasm of melanocytes. The malignant melanoma (MM) involving other organs is almost always metastatic. We report one case of primary MM of the lung with metastases to brain and bone. A rounded, well-demarcated and multi-lobulated mass lesion was observed in computed tomography. Histopathologic findings were compatible to MM. [18F]-fluorine-2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) revealed FDG-uptake at right upper lobe of lung and additionally at 3rd. thorocic vertebra, left ilium and left proximal femur, suggesting the hematogenous bone metastases. Brain magnetic resonance imaging showed two metastatic tumors in both frontal lobes. To date, a few cases of primary MM of lung have been reported in the English literature. Furthermore, this report uncovers quite advanced case compared to previous ones and provides radiologic and histopathologic speculations on MM in lung and suggests the availability of PET CT in diagnosis of advanced MM with multiple metastases.
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