Endobronchial metastasis of uterine cervical cancer
의약학 > 내과학
( Eun Jung Ko ) , ( Jisu Oh ) , ( Ji Su Kim ) , ( Yeong Min Leem ) , ( Suk Pyo Shin ) , ( Chi Young Park ) , ( Won Jung Hong ) , ( Hye Cheol Jeong )
대한내과학회 추계학술발표논문집 2011년, 제2011권 제1호, 209(총1페이지)
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    Endobronchial metastases are an uncommon complication of malignant tumors. The vast majority is secondary to carcinoma of the breast, colorectum and kidney, or melanoma. Endobronchial metastasis from uterine cervical cancer defines a bronchoscopically visible non pulmonary neoplasm metastatic to the bronchus and histologically identical to cervical cancer. Endobronchial metastasis of uterine cervical cancer is a very rare disease, and in this report we described a case about that. A 46 year-old female presented at our practice with one month history of a dry cough associated with dyspnea and chest discomfort. She had cervical cancer stage IIb treated with five-cycled neoadjuvant chemotherapies and radical hysterectomy with bilateral pelvic lymphandectomy. A chest x-ray and chest computed tomography (CT) scan revealed ill-defined large mass in left upper lobe and left hilum with mediastinal invasion (left pulmonary artery) and left upper lobar bronchial obstruction. Bronchoscopy demonstrated complete obstruction of the left upper lobe bronchus by a tumor. Bronchoscopic biopsy was performed and the specimen was consistent with squamous cell carcinoma (SCC). The immunohistochemical staining profile favoured a diagnosis of metastatic cervical SCC over one of primary lung SCC (thyroid transcription factor-1 (TTF-1) negative, HPV DNA Chip examination: Positive high risk 16). She was treated with radiation therapy as a palliative measure but died 4 months later.
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