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자연과학 > 생물
저자
고선근 ( Sun Kun Ko )
발행기관
한국환경생물학회
간행물정보
환경생물학회지(환경생물) 2012년, 제30권 제3호, 231~237쪽(총7쪽)
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23201136.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Toxicity of Ni2+ and Tebuconazole were investigated via FETAX (Frog Embryo Teratogenesis Assay-Xenopus) protocol using domestic frog embryos. Embryos of Black-spotted pond frog, Rana nigromaculata, were incubated and toxic effects of Ni2+ and Tebuconazole were investigated by probit analysis. As a result, mortality and malformation rates were increased and larval body length was decreased in a dose dependant manner of Ni2+ and Tebuconazole. The half maximal effective concentration (EC50) of Ni2+ and Tebuconazole were 0.07, 12.7 mg L-1, respectively and the half maximal lethal concentration (LC50) of Ni2+ and Tebuconazole were 4.2, 39.1, respectively. The teratogenic index (TI) were 61.4 in Ni2+ and 3.1 in Tebuconazole, respectively. These results reveals that Ni2+ and Tebuconazole suppress the development of Black-spotted pond frog embryos at the low concentration as showing teratogenic effects in other assay system. Therefore, teratogen assay system using the Rana nigromaculata embryos could be useful as a tool to evaluate the toxicity of the pollutants in environment.
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