생쥐 치아 발생과정 중 법랑질모세포에서 Dynamin II 발현
분야
의약학 > 기초치의학
저자
최정미 ( Jung Mi Choi ) , 문덕환 ( Deog Hwan Moon ) , 이정화 ( Jung Hwa Lee )
발행기관
한국치위생과학회
간행물정보
치위생과학회지 2012년, 제12권 제5호, 486~492페이지(총7페이지)
파일형식
1g100665.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Immunostaing intensity of Dynamin II protein in ameloblast during mouse tooth development showed a significant increase of 48% at the postnatal day 3 and a significant increase of 50% at the postnatal day 5 as compared with the postnatal day 1, but showed a significant decrease of 16% at the postnatal day 7 and a significant decrease of 12% at the postnatal day 10 as compared with the postnatal day 1. From the above results, Dynamin II had relevance to secretion of amelogenin, ameloblastin, enamelin and matrix metalloproteinase-20 proteins for enamel formation in ameloblast. Dynamin II may be involved in the transport of vesicles containing proteins for enamel formation through the acceleration of vesicular formation and may be had a good possibility of secretory regulation of proteins for enamel formation in ameloblast. Therefore, Dynamin II have potential for being used in the field of gene theraphy for periodontal disease and in the regeneration for enamel and dentin tissues lost to dental caries.
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