Sarcoidosis Presenting with Massive Pleural Effusion and Elevated Serum and Pleural Fluid Carbohydrate Antigen-125 Levels
분야
의약학 > 내과학
저자
( In Seon Lee ) , ( Sae Byul Kim ) , ( Chan Soo Moon ) , ( Sung Mo Jung ) , ( Song Yee Kim ) , ( Eun Young Kim ) , ( Ji Ye Jung ) , ( Young Ae Kang ) , ( Young Sam Kim ) , ( Kyu Kim ) , ( Joon Chang ) , ( Moo Suk Park )
발행기관
대한결핵 및 호흡기학회
간행물정보
Tuberculosis and Respiratory Diseases 2012년, 제73권 제6호, 320~324쪽(총5쪽)
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0y909697.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    A 55-year-old woman was admitted for an elevated serum carbohydrate antigen-125 (CA-125) level, and a left pleural effusion, which were detected at a routine health examination. Computed tomography of the chest was performed upon admission, revealing extensive bilateral paratracheal and mediastinal lymph node enlargement with a massive left-sided pleural effusion. Subsequent analysis of the pleural fluid demonstrated consistency with an exudate, no evidence of malignant cells, and a normal adenosine deaminase. However, the pleural fluid and serum CA-125 levels were 2,846.8 U/mL and 229.5 U/mL, respectively. A positron emission tomography did not reveal any primary focus of malignancy. Finally, a surgical mediastinoscopic biopsy of several mediastinal lymph nodes was performed, revealing non-necrotizing granulomas, consistent with sarcoidosis. After a month of treatment of prednisolone, the left pleural effusion had resolved, and after 2 months the serum CA-125 level was normalized.
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