Original Article : Long-Term Outcome of Cystic Lesions in the Pancreas: A Retrospective Cohort Study
분야
의약학 > 내과학
저자
( Dong Won Ahn ) , ( Sang Hyub Lee ) , ( Jai Hwan Kim ) , ( Won Jae Yoon ) , ( Jin Hyeok Hwang ) , ( Jin Young Jang ) , ( Ji Kon Ryu ) , ( Yong Tae Kim ) , ( Sun Whe Kim ) , ( Yong Bum Yoon )
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대한간학회
간행물정보
Gut and Liver 2012년, 제6권 제4호, 493~500페이지(총8페이지)
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27405407.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Background/Aims: The management guidelines for cystic lesions of the pancreas (CLPs) are not yet well established. This study was performed to document the long-term clinical outcome of CLPs and provide guidelines for the management and surveillance of CLPs. Methods: In this retrospective cohort study, an additional follow-up was performed in 112 patients with CLPs enrolled from 1998 to 2004 during a previous study. Results: During follow-up for the median period of 72.3 months, the size of the CLPs increased in 18 patients (16.1%). Six of these patients experienced growth of their CLPs after 5 years of follow-up. Twenty-six patients underwent surgery during follow-up, and four malignant cysts were detected. The overall rate of malignant progression during follow-up was 3.6%. The presence of mural nodules or solid components was independently associated with the presence of malignant CLPs. Seven patients underwent surgery after 5 years of follow-up. The pathologic findings revealed malignancies in two patients. There was only one pancreas-related death during follow-up. Conclusions: The majority of CLPs exhibit indolent behavior and are associated with a favorable prognosis. However, long-term surveillance for more than 5 years should be performed because of the potential for growth and malignant transformation in CLPs. (Gut Liver 2012;6:493-500)
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