영문초록
Background: Despite recent improvements in survival outcome after ABO incompatible (ABOi) adult living donor liver transplantation (ALDLT), concerns about the incidence of biliary stricture (BS) still exist. However, reports on the actual incidence of BS have been scarce. Methods: From November 2008 to August 2011, 77 cases of ABOi ALDLTs have been performed. We compared patient and graft survival and BS-free survival rates (BSFSR) between these ABOi ALDLTs and 734 ABO compatible (ABOc) ALDLTs performed during the same period. We also analyzed characteristics of BS in ABOi ALDLT. Results: There was one mortality (1.3%) and one re-transplantation (due to small-for-size graft syndrome) among 77 cases of ABOi ALDLTs. Overall, 1-, 2-, and 3-year patient survival rates were 94.8%, comparable to ABOc ALDLTs (93.7%, 90.1%, 90.1%, P=0.20). BS occurred in 11 (13.8%) ABOi ALDLT patients. There were no significant differences in 1-, 2-, and 3-year BSFSR between ABOi and ABOc ALDLT patients (87.5% vs. 88.1%, 83.4% vs. 87.5%, and 83.4% vs. 86.4%, P=0.55). Among 10 patients with BS, four patients showed diffuse multiple intrahepatic strictures, which were linked to the death of two patients. Conclusions: The survival outcome of ABOi ALDLT is comparable to ABOc ALDLT. The incidence of BS of ABOi ALDLT was not superior to that of ABOc ALDLT. However, ABO incompatibility is related to the development of diffuse multiple intrahepatic BSs (rarely seen in ABOc ALDLT) and can cause graft failure and patient death.
추천자료
신장이식 kidney transplantation
[간호, 간호사례] 가와사키병 간호 사례, 위암 간호 사례, 실어증환자 간호, 수혈 간호, 뇌수술 간호, C-sec 간호 심층 분석
[간호, 환자간호] 시각장애환자의 간호, 실어증환자의 간호, 제왕절개환자의 간호, 쇼크환자의 간호, 수혈환자의 간호, 신경계수술환자의 간호, 신장이식환자의 간호에 관한 분석
[아동간호학실습]신생아 패혈증 케이스-TTN
[사회문제론] 장기매매에 대해서
A++ 호흡기계 의학용어, 약어 해설
[의학] 윌슨병[Wilson\`s disease, Hepatolenticular degeneration]에 관해서
[병리학] 면역 기능과 면역 세포
[의료사회사업론] 소아만성신부전증 사례
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