원저 : 음곡(KI10) 편축 약침의 LPS 유도 급성신장염 억제 효과
분야
의약학 > 기초한의학
저자
임윤경 ( Yun Kyoung Yim )
발행기관
경락경혈학회
간행물정보
Korean Journal of Acupuncture 2012년, 제29권 제4호, 598~603페이지(총6페이지)
파일형식
1x500652.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Objectives: This study aimed to evaluate the effects of Polygoni avicularis Herba Herbal-acupuncture(PaH-HA) at KI10(Umgok) on nephritis induced by lipopolysaccharide(LPS) in rats. Methods: Rats were allocated into normal, control, and 3 experimental groups. The rats in the control group were intra-peritoneally injected with LPS for nephritis induction. The rats in the groups of experiment 1, experiment 2, and experiment 3 were treated with single needle prick, saline injection, and PaH-HA, respectively at KI10 three times for a week and then injected with LPS. To evaluate the effects of PaH-HA at HI10, WBC count in blood, serum CINC-1, renal TNF-α and renal MPO were measured. Results: Needle prick at KI10 suppressed the increase of WBC in blood and CINC-1 in serum of LPS-stimulated rats. Saline injection at KI10 suppressed the increase of WBC in blood. PaH-HA at KI10 suppressed the increase of WBC in blood, CINC-1 in serum, and MPO in kidney of LPS-stimulated rats. Conclusions: PaH-HA at KI10 has an anti-inflammatory effect on LPS-induced nephritis in rats and there may be a synergism between KI10(Umgok) stimulation and PaH-HA Solution.
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