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의약학 > 기타(의약학)
저자
권경훈 ( Kyoung Hun Kwon ) , 정해원 ( Hai Won Chung )
발행기관
서울대학교 인구의학연구소
간행물정보
인구의학연구논집 2012년, 제25권 42~48페이지(총7페이지)
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0y500292.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    The next generation sequencing (NGS) is faster and a lower cost new sequencing technique getting huge-large scale fragment, called reads, and sequence data than traditional sequencing. NGS technologies include a number of methods that are grouped broadly as template preparation, sequencing and imaging, and data analysis. Recently available next generation sequencer are the GS-FLX (Roche). Genome Analyzer (Illumina), and SOLiD (Life Technologies). However, the NGS produces much shorter sequences and large volumes of reads compared to conventional sequencing, whereby huge amounts of short reads are aligned onto a reference. For fast mapping of the massive amounts of short reads, a lot of mapping algorithms and programs have been developed. In this article, we introduce NGS technique and application of NGS.
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