The Effect of Platelet-Rich Plasma on Proliferation of Dental Stem Cells Derived from Human Tooth
분야
의약학 > 의공학
저자
( You Young Jo ) , ( Hee Jung Lee ) , ( Pill Hoon Choung ) , ( Byoung Moo Seo ) , ( Ui Lyong Lee )
발행기관
한국조직공학·재생의학회
간행물정보
조직공학과 재생의학 2006년, 제3권 제4호, 440~444페이지(총5페이지)
파일형식
2a800123.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    To investigate effect of platelet-rich plasma(PRP) on proliferation and differentiation of postnatal stem cells derived from human dental tissues, we isolated stem cells from dental tissues such as dental pulp, periodontal ligament, and surrounding mandibular bone. The isolated dental stem cells were tested on colony forming ability, proliferation, and ALP activity at different concentration of PRP. All of dental stem cells showed high proliferation as increased concentration of PRP. On the contrary, high concentration PRP such as 5% inhibited proliferation of stem cells. These results suggest that the proper concentration of PRP can be utilized to accelerate the proliferation of human dental stem cells.
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