Feature Article : Protein and Gene Delivery in Tissue Engineering

분야: 의약학 > 의공학
저자: ( In Yong Kim ) , ( Jong Hoon Chung ) , ( Yun Jaie Choi ) , ( Chong Su Cho )
발행기관: 한국조직공학·재생의학회
간행물정보: 조직공학과 재생의학 2008년, 제5권 제4호, 671~677페이지(총7페이지)
파일형식: 2a800265.pdf [무료 PDF 뷰어 다운로드]
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연관 논문

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Engineering the Cellular Protein Secretory Pathway for Enhancement of Recombinant Tissue Plasminogen Activator Expression in Chinese Hamster Ovary Cells: Effects of CERT and XBP1s Genes

Feature Article : Thermosensitive Hydrogels for Tissue Engineering

영문초록

In regenerative medicine, growing demand for tissues and organs has led to the rapid development of tissue engineering as an alternative. To improve functional scaffold, many biomaterials serve dual purposes; in addition to providing cell support, cutting-edge scaffolds biologically interact with adhering and invading cells and effectively guide cellular growth and development by releasing bioactive proteins and genes. For achieving the ambitious goal of tissue regeneration and replacement, it is more important to understand the basic principles of protein and gene delivery as well as design of the system required by using proper biomaterials. This review covered the requirement in the materials choice, the strategies, the main techniques for producing proteins and genes releasing scaffolds.

#Tissue engineering # protein delivery # gene delivery # scaffold # biomaterial

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