알긴산나트륨함량에 따른 BSA/PLGA미립구에서의 BSA방출거동
분야
의약학 > 의공학
저자
구정 ( Jung Ku ) , 박종학 ( Jong Hak Park ) , 안식일 ( Sik Il Ahn ) , 이준희 ( Jun Hee Lee ) , 김윤태 ( Yun Tae Kim ) , 김대성 ( Dae Sung Kim ) , 김원 ( Won Kim ) , 신형식 ( Hyung Shik Shin ) , 이종문 ( John M. Rhee ) , 강길선 ( Gil Son Khang )
발행기관
한국조직공학·재생의학회
간행물정보
조직공학과 재생의학 2008년, 제5권 제4호, 723~728페이지(총6페이지)
파일형식
2a800270.pdf [무료 PDF 뷰어 다운로드]
  • ※ 본 자료는 참고용 논문으로 수정 및 텍스트 복사가 되지 않습니다.
  • 구매가격
    4,500원
    적립금
    135원 (구매자료 3% 적립)
    이메일 발송  스크랩 하기
    자료 다운로드  네이버 로그인
    영문초록
    We developed the BSA loaded PLGA microspheres using a sodium alginate and water-in-oil-water (W/ O/W) solvent evaporation method for sustaining release of BSA and recognized the release behavior according to sodium alginate concentration. We characterized the surface and the cross-section morphology of prepared PLGA microspheres by the SEM and behavior of BSA release from microspheres for 45 days by BCA assay method. After 45 days, the molecular weight change of PLGA was measured by GPC. The surface of microspheres appeared sphere shape and had may pores. According to sodium alginate concentration increasing, the size of microspheres increased and release rate of BSA from microspheres decreased. These results show that the change of sodium alginate concentration can control the release behaviors.
    사업자등록번호 220-87-87785 대표.신현웅 주소.서울시 서초구 방배로10길 18, 402호 대표전화.070-8809-9397
    개인정보책임자.박정아 통신판매업신고번호 제2017-서울서초-1765호 이메일 help@reportshop.co.kr
    copyright (c) 2009 happynlife. steel All reserved.