Original Paper : Migrational Behavior of Human Melanoma towards Polymeric Chemoattractants
분야
의약학 > 의공학
저자
( Kyu Nam Park ) , ( Han Joon Kim ) , ( Jung Hee Wee ) , ( Who Kyong Lee ) , ( Heung Jae Chun ) , ( Ju Woong Jang ) , ( Richard B Beard )
발행기관
한국조직공학·재생의학회
간행물정보
조직공학과 재생의학 2008년, 제5권 제4호, 927~931페이지(총5페이지)
파일형식
2a800295.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    In order to understand the molecular mechanisms of chemotaxes through reactive oxygen species(ROS), the polymeric chemoattractants with free radical generating compounds were prepared, and the migrational behavior of melanoma cells towards the samples was investigated using a Boyden chamber assay. The samples with quinoid compounds had an enhanced melanoma cells migration than control. The migrational abilities of cells were further increased when the free radicals on the surface of samples were activated with blood plasma.
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