Case Reports : Hepatoid carcinoma of the ovary without staining for alpha-fetoprotein
의약학 > 산부인과학
( Tae Hyun Kim ) , ( Byoung Gie Kim ) , ( Duk Soo Bae ) , ( Min Ji Kim ) , ( Tae Joong Kim ) , ( Ji Hee Sung ) , ( Hyang Gi Park )
Obstetrics & Gynecology Science 2013년, 제56권 제1호, 41~44페이지(총4페이지)
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    Primary hepatoid carcinoma of the ovary (HCO) is a rare type of ovarian tumor that resembles hepatocellular carcinoma both histologically and immunohistochemically in its staining for alpha-fetoprotein (AFP). We describe a 51-year-old woman who presented to our hospital complaining of abdominal pain. Computed tomography scan revealed a large tumor in the pelvis. She underwent total hysterectomy and bilateral salpingo-oophorectomy with tumorectomy. A right ovarian mass measuring 9×8×6 cm was found. Histological diagnosis was hepatoid carcinoma of the right ovary. But, immunohistochemically, tumor cells were not immunoreactive for AFP and there was no elevation of serum AFP level. This is the first report of an ovarian carcinoma with typical histologic features of HCO with negative staining for AFP and normal level of serum AFP in the world.
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