미역(Undaria pinnatifida) 물 추출물의 염증 억제 활성
분야
농학 > 농화학
저자
정다현 ( Da Hyun Jeong ) , 김꽃봉우리 ( Koth Bong Woo Ri Kim ) , 강보경 ( Bo Kyeong Kang ) , 정슬아 ( Seul A Jung ) , 김현지 ( Hyun Jee Kim ) , 정희예 ( Hee Ye Jeong ) , 박시우 ( Si Woo Bark ) , 안동현 ( Dong Hyun Ahn )
발행기관
한국응용생명화학회(구 한국농화학회)
간행물정보
Journal of Applied Biological Chemistry 2012년, 제55권 제4호, 221~225페이지(총5페이지)
파일형식
06005964.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    The anti-inflammatory effects of Undaria pinnatifida water extract (UPWE) were investigated using lipopolysaccharide -induced inflammatory response in this study. To examine the potential anti-inflammatory properties of UPWE, the cell proliferation, nitric oxide (NO), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and IL-1β were measured. As a result, there was no cytotoxicity in the macrophage proliferation treated with UPWE compared to the control. NO levels decreased with increasing concentration of UPWE. Moreover, the secretion of IL- 6, TNF-α and IL-1β were suppressed in a dose-dependent manner, and IL-6 inhibition activities were over 50% at 0.1%. These results suggested that UPWE may have significant effects on inflammatory factors and be a potential anti-inflammatory therapeutic materials.
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