본문 : 인체피부섬유아세포에서 녹차,백차,홍차 열수추출물의 콜라겐 합성능 비교 연구
분야
자연과학 > 가정
저자
김상남 ( Sang Nam Kim ) , 이채명 ( Chae Myoung Lee ) , 강성례 ( Sung Rye Kang ) , 김영철 ( Young Chul Kim )
발행기관
대한미용학회(구 대한미용과학회)
간행물정보
대한미용학회지 2012년, 제8권 제4호, 227~233페이지(총7페이지)
파일형식
1d300313.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    This study was conducted to evaluate the collagen synthetic abilities of water extracts of green tea (GT), white tea (WT) and black tea (BT) in human dermal fibroblasts. In MTT assay, the maximum permissible level for GT, WT and BT was over 200μg/mL, and that for EGCG was 50μg/mL. In the experiment of type-I procollagen synthetic ability, TGF-β1 (positive control) increased it by 179% (p/0.001) at the concentration of 5 ng/mL, compared to the control group. At the concentrations of 12.5, 25, and 50μg/mL, EGCG increased it by 49.3, 80.1 (p/0.01), and 141.6% (p/0.001), GT increased it by 8.3, 48.1, and 98.5% (p/0.01), WT increased it by 10.3, 38.6, 110.4% (p/0.05), and BT increased it by 89.5 (p/ 0.01), 96.9 (p/0.01), and 114.5% (p/0.01), respectively. The order of high to low sequence for the collagen synthetic ability was EGCG¤BT¤WT and GT. It was conformed that GT, WT and BT had high collagen synthetic abilities, and they could be a useful functional natural source for the anti-wrinkle cosmetic materials.
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