Feature Article : In Vitro Effects of Electromagnetic Field Stimulation on Cells in Tissue Engineering
분야
의약학 > 의공학
저자
( Ki Taek Lim ) , ( Jang Ho Kim ) , ( Hoon Seon Woo ) , ( Hyun Mok Son ) , ( Soo Jung Baik ) , ( Joo Young Park ) , ( Soung Hoo Jeon ) , ( Eun Suk Kim ) , ( Yun Hoon Choung ) , ( Chong Su Cho ) , ( Pill Hoon Choung ) , ( Jong Hoon Chung )
발행기관
한국조직공학·재생의학회
간행물정보
조직공학과 재생의학 2009년, 제6권 제4호, 675~684페이지(총10페이지)
파일형식
2a800390.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    The effects of electromagnetic fields and magnetic fields on cell proliferation is currently an active area of interest. In light of the widespread applications of electromagnetic stimulation for the clinical therapy of periodontal disease, it is likely that electromagnetic stimulation could have an important influence on key functional activities of osteoblasts in alveolar bone. The purpose of our research is to develop an optimized and appropriately characterized non-invasive treatment for alveolar bone tissue engineering using pulsed electromagnetic field stimulation. Based on the reviewed literature, the effects of electromagnetic field stimulation on cells may alter membrane functions such as ion channels, ligand binding, and alterations in the density and distribution of receptors. Each of these mechanisms has the ability to affect transmembrane signaling. Therefore, The oscillating ions during forced-vibration can exert mechanical forces-pressure, on the plasma membrane, capable to upset the membranes electrochemical balance under certain conditions by opening or closing mechanically gated channel proteins like some Ca2+ influx channels. In light of the widespread applications of electromagnetic fields stimuli for the clinical therapy of periodontal disease, it is likely that electromagnetic fields stimuli could have an important influence on key functional activities of osteoblasts in alveolar bone.
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