Upon fixture implantation, the first interaction between the fixture and the host organism begins at the surface of the fixture as it encounters the blood and the interstitial fluid of the host. Especially, molecules including proteins, derived from the body fluid, adsorbs to the surface of the fixture, and the process of it acts as a signal forwarding following biological reactions, rendering various cells to go through adhesion and reorganization, which enables osseointegration of the fixture within the bone structure. In this review, adhesion proteins that are known to adsorb to the implant surface in initial stage are focused. First, the general process, mediated through adhesion proteins such as integrins in the micro-environment consisting of the surface and cells, are reviewed. Next, the studies of adhesion proteins in vitro and in vivo are discussed. Lastly, this paper will describe how these proteins can affect cell spreading, proliferation and differentiation in the implant- tissue interface. An understanding of the special features of the adhesion proteins and their receptors is a prerequisite for the development of novel implant surfaces.
의료산업 - 생체고분자와 시장동향
[공학] 의료용 고분자 재료
[재료학] 인체 고관절 수술과 생체 재료
[화공생명] 단백질의 분리와 분석(1-D 전기영동)
[미생물학, 생물학, 생리학, 멸균과 소독, 간염] 멸균과 소독 그리고 감염
[효소, 효소활용, 세제산업, 섬유산업] 효소의 정의, 효소의 구조, 효소의 특성과 효소의 활성저해 요인, 효소의 작용 및 세제산업의 효소활용 사례, 섬유산업의 효소활용 사례 심층 분석
[친환경 소재] 친환경 의복의 정의와 실태, 문제점 및 해결방안