In this study, we proposed a novel method which has several merits: guaranteed interconnectivity, solvent free, and unnecessary expensive devices. For the proposed novel method named as Wire-Network Molding, firstly, we prepare a mold with designed shape. Secondly, rectangular wires with thickness size 300 μm, 400 μm or 620 μm are inserted to make space for interconnected pore. After that, melted PCL (polycaprolactone) which is one of synthetic polymers with biocompatibility is filled in the mold and the mold is cooled at room temperature. Subsequently, wires are separated from the mold and the mold is removed from PCL. Consequently, the remained PCL has interconnected pores with a configuration of wire-network. To analyze the compressive modulus of the fabricated scaffold, UTM compression test is carried out. Moreover, we compare the compressive modulus of the fabricated scaffold with that of bio-plotter scaffold. Additionally, for scaffolds with 300 μm, 400 μm pore size, cell culture experiments are carried out using human.