Original Article : Correlation between Endoscopic and Histological Diagnoses of Gastric Intestinal Metaplasia
의약학 > 내과학
( Ji Hwan Lim ) , ( Nayoung Kim ) , ( Hye Seung Lee ) , ( Gheeyoung Choe ) , ( So Young Jo ) , ( Ilyoung Chon ) , ( Chiun Choi ) , ( Hyuk Yoon ) , ( Cheol Min Shin ) , ( Young Soo Park ) , ( Dong Ho Lee ) , ( Hyun Chae Jung )
Gut and Liver 2013년, 제7권 제1호, 41~50페이지(총10페이지)
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    Background/Aims: Intestinal metaplasia (IM) is a premalignant condition. This study aimed to evaluate the correlation between endoscopic and histological findings of IM. Methods: The cases of IM were graded by conventional endoscopy, and biopsies were taken from the antrum and body of 1,333 subjects for histological IM diagnosis. Multivariate analyses were performed to identify the factors that affect the sensitivity of endoscopic IM diagnosis. Results: The sensitivity/ specificity of endoscopic IM diagnosis based on histology was 24.0%/91.9% for the antrum and 24.2%/88.0% for the body. As indicated by multivariate analysis, the presence of endoscopic atrophic gastritis (AG) (odds ratio [OR], 4.73; 95% confidence interval [CI], 2.07 to 10.79) and the activity of mucosal inflammation (OR, 2.21; 95% CI, 1.08 to 4.54) were associated with the sensitivity of endoscopic IM diagnosis in the antrum, while the presence of endoscopic AG (OR, 8.02; 95% CI, 4.55 to 14.15), dysplasia (OR, 2.40; 95% CI, 1.07 to 5.39), and benign gastric ulcers (OR, 0.35; 95% CI, 0.15 to 0.081) were associated with the sensitivity of endoscopic IM diagnosis in the body. Conclusions: As the sensitivity of endoscopic IM diagnosis was low, a high index of suspicion for IM is necessary in the presence of atrophy, and confirmation by histology is also necessary. (Gut Liver 2013; 7: 41-50).
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