The purpose of this study was to evaluate the influence of Er:YAG laser irradiation on the microshear bond strength (μSBS) of three single-step adhesive systems to dentin. Materials and Methods: The occlusal dentin surfaces of 30 extracted teeth were exposed. Samples were divided into six groups according to laser irradiation of dentin surface and type of single-step adhesive system (LP group: Adper Prompt L-Pop (3M ESPE Dental Products), LP-L group: Er:YAG laser (KEY Laser 3, KaVo)+Adper Prompt L-Pop, GB group: G-Bond (GC Corporation), GB-L group: Er:YAG laser+G-Bond, AB group: ALL-Bond SE (Bisco Inc.), AB-L group: Er:YAG laser+ALL-Bond SE). The bonded specimens were subjected to μSBS test, and the resin-dentin interfaces were observed under field emission scanning electron microscope. Results: There were no significant differences among the μSBS of LP, GB, and AB groups, whereas the μSBS of the LP-L and AB-L groups were significantly higher than that of the GB-L group (p<0.05). More adhesive failures were seen in the laser-irradiated groups than in the non-irradiated groups. All other groups, except the GB-L group, showed close adaptation at the interface of dentin and composite resin. Conclusion: Use of Er:YAG laser irradiation can reduce the bonding strength of composite resin to dentin depending on the type of single-step adhesive system.
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