증례 :헤르페스 포진형이 아닌 전신형 단순성 물집 표피박리증 1예
분야
의약학 > 피부과학
저자
고동엽 ( Dong Yeob Ko ) , 하승민 ( Seung Min Ha ) , 전수영 ( Su Young Jeon ) , 김대철 ( Dae Cheol Kim ) , 송기훈 ( Ki Hoon Song ) , 김기호 ( Ki Ho Kim )
발행기관
대한피부과학회
간행물정보
대한피부과학회지 2013년, 제51권 제3호, 219~222페이지(총4페이지)
파일형식
27728758.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    The other generalized type of epidermolysis bullosa simplex (EBS) is a genetic blistering skin disease, caused by a mutation of the genes encoding keratin 5 and 14. EBS starts at birth and is characterized by generalized blisters following a minor trauma that heals with hyperpigmentation. A 19-year-old man presented with 19-year history of multiple erythematous vesicles in a herpetiform arrangement on the trunk, axilla, and thigh with post-inflammatory hyper-pigmentations. On light and electron microscopy, the biopsy specimen showed intraepidermal blisters that formed within the basal keratinocyte. The serum from a patient with bullous pemphigoid antibody and laminin 5 antibody showed the linear deposition at the floor of the blister on immunofluorescence mapping study. On the basis of our clinical, microscopic, and immunofluorescence findings, we diagnosed the patient as having a generalized type of EBS. Herein, we report on an interesting case of the other generalized type of EBS. (Korean J Dermatol 2013;51(3):219∼222)
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