영문초록
Objectives: During several thousand years, Peucedanum Japonicum Thunberg has been considered as a vegetable side dish in Korea. There is folk knowledge that Peucedanum Japonicum Thunberg prevents vascular disease such as stroke. To identify the effects Peucedanum Japonicum Thunberg, we made up its extract and named it as KH020. Then, we employed common carotid artery ligation (CCAl) surgery for vascular dementia model (VDM), and two types doses of per os (per oral: p.o) treatment. Methods: To confirm prevention and recovery effects for vascular dementia, we treated two doses (100, 400 mg/kg) KH020 in male C57BL/6 mouse during 7 days. After treatment, animals were CCAl operated, and given time to recover. Then, animal were tested in a Y-maze and passive avoidance test. Results: Y-maze results demonstrated that cognition and memory performance were decreased in the VDM group, compared to the sham group. KH020 treatment abolished these effects significantly. The results from the passive avoidance test showed the same phenomenon, but it was not statically significant. Conclusions: Therefore, KH020 prevents the onset of vascular dementia. In future studies, we will evaluate KH020 in regard to alzheimer dementia.
추천자료
[치매환자미술치료] 치매환자에 대한 집단미술치료(집단미술요법) - 미술치료의 장점과 기대효과, 치매노인 미술치료요법의 효과, 집단미술치료기법
[치매환자의 재활] 치매환자에 대한 작업요법(작업요법의 개념과 목적 및 특징, 작업요법 접근방법, 작업요법 영역과 치료모형 및 치료과정, 치매환자에 대한 작업요법의 효과)
[사회보장] 고령사회의 도래와 노인간병문제
[보건기획] 노인 치매 예방 교육 및 프로그램개발
[치매노인케어] 치매의 개념(정의), 원인과 증상, 유형(형태), 유병률, 치료와 예방, 케어요령, 치매환자와 가족
[가족복지론] 돌봄 & 정서적 기능
[한의학]북한의 한의학
[사회복지] 노인장기요양보험 국가별 비교 및 민영화
[발달심라학] IQ와 다양한 삶의 분야와의 관계
[노인복지론] 노인건강보호