캐슬만병에서 기원하여 무증상 복강 내 종양으로 발현된 여포성 수상돌기 세포육종
분야
의약학 > 내과학
저자
황순오 ( Soon Oh Hwang ) , 이태훈 ( Ae Hoon Lee ) , 배상호 ( Sang Ho Bae ) , 조현득 ( Hyun Deuk Cho ) , 최강혁 ( Kang Hyug Choi ) , 박상흠 ( Sang Heum Park ) , 김창호 ( Chang Ho Kim ) , 김선주 ( Sun Joo Kim )
발행기관
대한소화기학회
간행물정보
대한소화기학회지 2013년, 제62권 제2호, 131~134페이지(총4페이지)
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07811554.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Follicular dendritic cell (FDC) sarcoma is an extremely rare malignant neoplasm arising from FDCs. The exact origin of FDCs remains unclear; both a hematopoietic lineage origin and a stromal cell derivation have been proposed. Proliferation of FDCs can lead to benign reactive lesions or generate neoplastic conditions. The lesions are most commonly found in lymph nodes and usually involve the head and neck area. Castleman`s disease is a rare non-neoplasitic lymphoproliferative disorder. Rare cases of hyaline-vascular Castleman`s disease have been associated with FDC sarcoma, but a clonal relationship has not been convincingly demonstrated. A pathway toward tumor evolution, beginning with hyperplasia and dysplasia of FDCs, has been proposed. Despite this known association between Castleman`s disease and FDC sarcoma, there have only been few reported cases of sarcoma arising as a complication of pre-existing Castleman`s disease, especially in abdominal lesions. We describe here a 51-year-old female with an FDC sarcoma arising from unicentric, hyaline-vascular type Castleman s disease in an intra-abdominal mass. Pathologically, the lesion showed a series of changes during the process of transformation from Castleman`s disease to FDC sarcoma. (Korean J Gastroenterol 2013; 62:131-134)
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