Pulmonary Function Is Associated with Frontal Lobe Function in Elderly Populationw
분야
의약학 > 내과학
저자
고성준 , 박지영 , 이홍열 , 이태훈 , 박종선 , 임효정 , 조영재 , 이재호 , 이춘택 , 김기웅 , 김태희 , 윤호일
발행기관
대한결핵 및 호흡기학회
간행물정보
대한결핵및호흡기학회 추계학술발표초록집 2012년, 제114권 201(총1페이지)
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    영문초록
    Background: There are reports of positive correlation between pulmonary function and cognitive function, but what domain of cognitive function is associated with pulmonary function is still unclear. Methods: We investigated the association between results of pulmonary function tests and various cognitive function tests in a community-based cohort of elderly people (≥65 years), the Korean Longitudinal Study on Health and Aging(KLoSHA). Results: Among the participants of KLoSHA cohort, 579 underwent pulmonary function tests and were analysed. Gender ratio was 306:273 (male:female) and their median age was 71. After adjusting for age, sex, height, smoking status, years of education, dementia, depression, and comorbidities, positive correlation was observed between Mini-mental state examination (MMSE) score and forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and peak expiratory flow rate (PEFR). Multivariate linear regression analyses revealed that FVC, FEV1, and PEFR was consistently associated with indices of frontal lobe function such as frontal assessment battery (FAB), verbal fluency, Boston naming test, and digit forward/backward tests. Conclusion: Pulmonary function is associated especially with frontal lobe function.
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