The Overlap Syndrome of Asthma and COPD: Its Prevalence and Clinical Characteristics
분야
의약학 > 내과학
저자
심재겸 , 민경훈 , 허규영 , 심재정 , 강경호
발행기관
대한결핵 및 호흡기학회
간행물정보
대한결핵및호흡기학회 추계학술발표초록집 2012년, 제114권 230(총1페이지)
파일형식
0y909963.pdf [무료 PDF 뷰어 다운로드]
  • ※ 본 자료는 참고용 논문으로 수정 및 텍스트 복사가 되지 않습니다.
  • 구매가격
    1,000원
    적립금
    30원 (구매자료 3% 적립)
    이메일 발송  스크랩 하기
    자료 다운로드  네이버 로그인
    영문초록
    Background: Although asthma and COPD have been accepted as different diseases, many elderly patients show clinical features of both asthma and COPD, so called "overlap syndrome". The purpose of our study was to examine the prevalence and clinical characteristics of the overlap syndrome (OS). Methods: We conducted a retrospective survey of patients above 40 years who had visited our hospital from January 2005 to June 2009 because of obstructive lung disease. Patients with structural lung disease were excluded and patients with short follow-up duration were excluded. Based on lung function profile, we classified subjects into COPD and OS groups, and analyzed their prevalence, demographics and lung function. Results: 2,105 subjects were included. 240 (11.4%) and 630 (29.9%) were found to have OS and COPD, respectively. The mean age was similar in both group (66.40 years vs 67.67 years, P=0.553) but age of symptom onset was earlier in OS group than COPD group (38.42 years vs 58.17 years, P<0.001). OS group showed lower baseline postbronchodilator FEV1 than COPD group (50.88% vs 57.65%, P=0.04). After additional treatment with tiotropium, OS and COPD groups showed significant improvement of postbronchodilator FEV1 (5.50%, P=0.012; 7.68%, P=.0.000). Conclusion: Certain proportion of aged patients have overlap syndrome. Although their symptom develops earlier and baseline lung function is worse, intensive treatment can improve lung function.
    사업자등록번호 220-87-87785 대표.신현웅 주소.서울시 서초구 방배로10길 18, 402호 대표전화.070-8809-9397
    개인정보책임자.박정아 통신판매업신고번호 제2017-서울서초-1765호 이메일 help@reportshop.co.kr
    copyright (c) 2009 happynlife. steel All reserved.