A Comparison of Healthcare-associated Pneumonia to Community- and Hospital-acquired Pneumonia in Patients Requiring Intensive Care Unit Admission
분야
의약학 > 내과학
저자
이홍열 , 박지영 , 이태훈 , 임효정 , 박종선 , 윤호일 , 이재호 , 이춘택 , 조영재
발행기관
대한결핵 및 호흡기학회
간행물정보
대한결핵및호흡기학회 추계학술발표초록집 2012년, 제114권 233(총1페이지)
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0y909968.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Background: Healthcare-associated pneumonia (HCAP) was proposed as a new category of pneumonia in the 2005 ATS/IDSA guidelines, emphasizing that patients with HCAP should be treated with broad-spectrum antibiotics directed at multidrug-resistant (MDR) pathogens. However, this concept continues to be a subject of controversy and there have been no studies about this issue in HCAP patients requiring intensive care unit (ICU) admission. Methods: A retrospective analysis of patients with HCAP who required ICU admission was conducted in a 16-bed medical ICU from March 2011 to June 2012. Clinical characteristics, microbiological distributions, treatment outcomes and prognosis of HCAP were compared to those with community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP). Results: A total of 140 patients (51 with CAP, 53 with HCAP, and 36 with HAP) were included for analysis. Median age of total patients (male, 78%) was 73.5 (19-92), mean APACHE II score was 25.1±9.4 and 134 (95.7%) were applied mechanical ventilator. The incidence of MDR pathogens (CAP, 16.0%; HCAP, 27.6%; HAP, 76.2%; P<0.001) was significantly different among three groups, especially between HAP and the others. Gram positive pathogens were less frequently cultured in HCAP patients (CAP, 68.0%; HCAP, 27.6%; HAP, 57.1%; P=0.009). There were no significant differences among three groups regarding appropriateness of initial antibiotics treatment, clinical outcomes and prognoses. Conclusions: HCAP in patients requiring ICU admission was more close to CAP, not HAP in terms of the frequency of MDR pathogens.
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