Widespread use of CT has increased the incidental detection of pulmonary nodules. We aim to analyze the clinical and radio-logic information for solitary pulmonary nodule to set up a clinical approaching strategy for the pulmonary nodules. This retrospective study was performed on 212 patients with pulmonary nodule diagnosed pathologically from January 2006 to December 2011 in a teaching hospital of Korea. Among total pulmonary nodules, benign nodules were 163 and malignant nodules were 49. The mean size of nodules in each group is 13.97±7.15 for malignant group and 11.27±7.00 for benign group (p=0.019). As for radiologic findings, as expected, star shape, irregular shape, spiculated margin, and presence of air-bronchogram were observed more frequently in malignant nodules (p＜0.05), while round shape, ellipsoidal shape, and smooth margin were de-tected more frequently in benign nodules(p＜0.05). However, these findings were not consistent in some groups; male gender, young aged person under 50 years old, and smokers, while the results from patient groups of female gender, old aged persons over 50 year olds, and non-smokers were relatively consistent with those of total patients. These results suggests that the clinical factors such as male, young age, and smoking history can be considered as one of reasons of early surgical resection, while the contrast cases can be considered as one of reasons for the image follow up for longer time in the management of pulmonary nodules, providing a rationale of the need for more individualized management guideline for pulmonary nodules.