In these days, paradigms of medical science have been changed from the treatment of diseases to predictive and preventive medicine. Discovery of Biomarkers certainly play an important role in the development of new diagnostic and therapeutic strategies for the future personalized medicine. High-quality biospecimens from the patients and normal subjects are indis-pensible for successes of these strategies. Therefore, biobanks, particularly dealing with human - derived biomaterials with good clinical data, can provide key resources to the basic scientist and researchers for their translational studies and discovery of new biomarkers. The Soonchunhyang University Bucheon Hospital Human Resource Biobank is a Collaborative Biobank of Korea and has been supported by a grant from the Korea Health 21 R&D Project, Ministry of Health and Welfare and Family, Republic of Korea.Up to date, 30,000 samples were collected. The bank has covered common respiratory diseases including asthma, COPD, lung cancer, tuberculosis as well as rare ones such as pulmonary fibrosis. The bank has collected lung tissues, bronchial epithelium, plasma, DNA bronchoalveolar lavage fluids, sputum and urine from over 10,000 donors. The mission is to collect and provide the human derived bio-resources for the scientist and physicians trying to discover the molecular and cellular biomarkers on non-commercial and academic base. The Bioresources in the SCH Biobank have been distributed to several academic institutions and NIH in Korea and also to international institutions such as deCODE genetics.