Lung Cancer in Young Adult Patients: Relationship between Lung Cancer and Smoking Status
의약학 > 내과학
( So Ri Kim ) , ( Yong Chul Lee ) , ( Chang Hun Lee ) , ( Yang Keun Rhee ) , ( Heung Bum Lee ) , ( Seoung Ju Park ) , ( Chi Ryang Chung ) , ( Seung Yong Park )
대한결핵 및 호흡기학회
대한결핵및호흡기학회 추계학술발표초록집 2012년, 제114권 288(총1페이지)
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    Lung cancer is the most common malignancy but there is relatively rare information for younger age group. We aim to analyze clinical characteristics of lung cancer of young patients and to discuss how smoking affect survival outcomes. A retro-spective analysis was done of patients with lung cancer under age 50 diagnosed between 1998 to 2011 in Chonbuk National University Hospital, Jeonju, Korea. The data with regard to demographics, presentation symptoms, presence of smoking, histo-logic type, staging, treatment modality and survival rate were obtained from medical records. Among the 242 patients, almost 55% of patients were smokers, and male to female ratio was 1.7: 1. Adenocarcinoma was the predominant histological subtype (59%) and there was more portion of squamous cell carcinoma with increasing age (p=0.010). Overall median survival rates of younger patients were 21.40 months and 5-year survival rate was 23%. The hazard ratio for smoker versus never smoker was 1.068 (95% CI, 0.607 to 1.878; p=0.820) and survival outcome indicated insignificant difference (p=0.361). Clinical charac-teristics of young adult in lung cancer patients tend to distinguish from general lung cancer population. Their smoking rate was lower and smoking didn`t affect survival outcomes. These results suggest that smoking is a less important cause for lung cancer patients in younger age.
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