Inflammatory pseudotumors (IP) of lung are rare benign tumors which are in fact, nonneoplastic unregulated growth of in-flammatory cells and composed of fibrous tissue with infiltration of plasma cells and lymphocytes. This tumor generally in-volves the lung parenchyma, but endobronchial involvement is extremely rare and physicians should be considered in the differential diagnosis of a solitary tumor in endobronchial cases. The precise origin of IP is not well known but its clonal changes suggest true neoplasm rather than a purely inflammatory or reactive lesion, and complete resection is accepted treat-ment of choice. Furthermore the exact nature between the IP and the lung malignancy and the concomitant cases were not reported. A 75-year old male patient complained of blood tinged sputum for 10 days. Simple chest radiography and chest spiral computerized tomography (chest CT) revealed right upper lung atelectasis. Bronchosocpy demonstrated R! B3 was near total occluded by the intraluminal mass. Two times of bronchoscopic biopsy were just nonspecific chronic inflammations Percutaneous transthoracic lung biopsy (TTB) was performed and confirmed IP with focal suppurative inflammation. Follow up chest CT demonstrated increasing the consolidation at the previous atelectatic right upper lung. Repetitive TTB was done and confirmed adenocarcinoma with solid pattern. We present a case report of a 75-year-old man with endobronchial IP combined adenocarcinoma. This case highlights that physicians should be regular follow up the remained IP cases looking for the hidden or concomitant lesions.