Recurrent Episodes of ABPA in a Healthy Young Adult: A Case Report
의약학 > 내과학
( Yu Ji Kim ) , ( Yong Chul Lee ) , ( So Ri Kim ) , ( Seung Yong Park ) , ( Yang Keun Rhee ) , ( Heung Bum Lee ) , ( Seoung Ju Park ) , ( Chi Ryang Chung )
대한결핵 및 호흡기학회
대한결핵및호흡기학회 추계학술발표초록집 2012년, 제114권 308(총1페이지)
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    The pathogenesis of allergic bronchopulmonary aspergillosis (ABPA) is composed of both the compromised host defense, which causes the colonization of Aspergillus in the bronchial tree, and the allergic host reaction to Aspergillus antigen. ABPA is diagnosed by the criteria of Rosenberg and Patterson in 1977. In addition, the staging system for ABPA has been presented previously to assist in the evaluation and management of ABPA as follows; (1) acute, (2) remission, (3) exacerbation, (4) corti-costeroid-dependent asthma, and (5) pulmonary fibrosis. However, it had been uncertain whether patients with ABPA in re-mission were at risk for recurrences and whether the characteristics or management strategies of recurrent ABPA are different from first episode. Herein, we report a case of a 23-year-old man with asthma presenting repeated recurrence of ABPA for 4 years, though he is an immunocompetent and healthy young adult. His response to the medical treatment with oral glucocorti-coid and itraconazole was very excellent at each episode. We discuss our case with the previous literatures focusing on the clinical and radiologic features as well as the therapeutic response of recurrent ABPA.
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