Acanthopanax had .recently been a lot of interest, therefore we investigated its chemical component and efficacy by research of literatures. To study a relation pharmacological action of chemical component and effects as we consider medical effect. First we searched books, research paper, internet site. Second, Keywords were searched Acanthopanax, Acanthopanax Cortex Radicis, effects of acanthopanax, extract of acanthopanax (HPLC,LC-MS), chiisanoside, Lignan (sesamin, helioxanthin, savinin, taiwanin C, e1eutheroside E, acanthoside D), Pimaric acid, stigmasterol, syringing, hyperin, caffeic acid. Third, in this key word arranqement a medical effect paper. 1) effects of acanthopanax 2) chemical component of acanthopanax. Results obtained in this study that active components of Acanthopanax are chiisanoside, Lignan (sesamin, helioxanthin, savinin, taiwanin C, eleutheroside E, acanthoside D), Pimaric acid, stigmasterol, syringing, hyperin, caffeic acid. These components suggest that acanthopanax may be used in the clinical field against several diseases, such as antacid, anti-inflammatory, antitumor effect, anti-depressant, antiallergic, nephropathy, suppress of melanin pigment. We know that there are effect of oriental medicine and effect of Acanthopanax chemical compound. So, It studied efficacy`s of each compounds. First, pharmacological action of Acanthopanax are antioxidant effect, anti-cancer, antiallergic, suppress of melanin pigment, nephropathy, anti-depressant. Second, the reported that Lignan in Acanthopanax a component parts of sesamin have osteoporosis treatment effect, helioxanthin and savinin have liver protection effect, taiwanin C have anti-inflarnatory effect, eleutheroside E have robustness effectiveness, acantboside D have lipotropic effect. Third, the repored that Acanthopanax at component of Pimaric acid have antibacteria effect and anti- inflamatory effect, stigmasterol have immunosuppression effect, Syringin have liver protection and protection effect of a brain nerves. Fourth, in effects of Korean medicine of Acanthopanax on ``xinglxue action (行血作用), ``xiehuo action (瀉火 作用)``, ``zaoshi action 燥濕作用)``, ``buzhongyijing (補中益精)``, ``qingshennailao (輕身耐老)``, ``qufengshiYao (去風濕藥)`` efficacys concerned with anti-inflamatory, immunosuppression, anti-cancer, liver protection, boost the blood pressure.