Mycobacterium marinum is an atypical mycobacterium (ATM) and is an uncommon cause of skin and soft tissue infections associated with contact with contaminated water. Diagnosis is often delayed when only a conventional identification method is used. PCR amplification and direct sequencing is recently available method for rapid identification of ATM. We report a case of M. marinum infection identified by PCR and sequencing. A 56-year-old female was referred for multiple erythematous nodules on both forearms which appeared two months ago. Skin biopsy showed suppurative granulomatous inflammation, and AFB culture showed nontuberculous Mycobacteria. PCR and sequencing were performed, and the obtained sequences were compared to the database using BLAST. The sequences of 16S rRNA and rpoB could not differentiate between M. marinum and M. ulcerans, showing 100%homology to both. Identification was possible using the sequences of the tuf and hsp65 genes, showing both 100%homology to M. marinum, while 99.8%, 99.7% to M. ulcerans. The patient was treated with clarithromycin, rifampicin,and ethambutol for 6 months.
간호진단 폐결핵 케이스 pulmonary tuberculosis
증후군의 정의 및 종류, 원인, 증상, 대책, 최근 연구동향을 통한 나의 의견 정리
[유전] 유전병 레포트
[생명과환경] 한국인의 코로나 19 (신종 코로나 바이러스)에 대한 반응과 메르스에 대한 반응 (및 또는 가습기 살균제의 광범위한 사용으로 이끈 심리)의 공통점
[경영학] 바이오 산업 마크로젠 마케팅 전략 분석
[전염병] 호흡기계 전염병, 접촉성 전염병, 만성 전염병, 소화기계 전염병, 보건복지부 지정 전염병, 절지동물 매개 전염병 심층 분석
공중보건학 요약(보건계열 국가고시 대비, 25장 완벽 정리)입니다.
[세균학] 균의 동정
[의학] 후천성면역결핍증 AIDS