원저 : 일개 응급의료센터에 내원한 15세 미만 소아 발열 환자에서 프로파세타몰 정맥주사의 해열 효과
분야
의약학 > 외과학
저자
천지만 ( Ji Man Chun ) , 제상모 ( Sang Mo Je ) , 박광호 ( Kwang Ho Park ) , 배진건 ( Jin Kun Bae ) , 정태녕 ( Taen Young Chung ) , 김의중 ( Eui Chung Kim ) , 최성욱 ( Sung Wook Choi ) , 김옥준 ( Ok Jun Kim )
발행기관
대한응급의학회
간행물정보
대한응급의학회지 2015년, 제26권 제1호, 82~88페이지(총7페이지)
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18403175.pdf [무료 PDF 뷰어 다운로드]
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    영문초록
    Purpose: Fever is one of the most common symptoms in children visiting the emergency department. When oral antipyretics use is limited, IV antipyretics may be necessary for control of fever. In this study, we examined the current status of use and antipyretic effect of propacetamol, a pre-cursor of acetaminophen, in fever management for children of age younger than 15 in an emergency center. Methods: We reviewed medical records of 101 patients who were prescribed IV propacetamol from September 1st to December 31st in 2013. Among these patients, 59 chil-dren received propacetamol via intravenous injection for control of fever. We investigated variable data including age, sex, weight, chief complaint, reason for use of intra-venous propacetamol, history of liver disease, and body temperature before the injection. In addition, to examine the antipyretic efficacy of IV propacetamol, we thoroughly investigated administration dose, number of injections, use of other antipyretics, other antipyretic therapy (ex. like tepid massage or ice bag), fever clearance time, etc. Results: Intravenous propacetamol at a dose of 26.16 mg/kg was used in 59 patients and fever was controlled under 38.C within 2 hours in 39 patients (66.1%). Fever was relieved under 38.C within 4 hours or general condi-tion was improved in 49 patients (83.0%). Conclusion: In this study, we examined the antipyretic effi-cacy of intravenous propacetamol in management of fever for children younger than 15 years of age in an emergency center. Optimized uses of intravenous propacetamol according to age and weight were effective for pediatric patients with fever who cannot swallow oral medications.
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