P222 : A case report of angioleiomyoma on vulva
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Angioleiomyoma is an uncommon benign tumor which arise from vascular smooth muscle. It usually has vascular structures surrounded by proliferated smooth muscle with well-demarcated nodule microscopically. Affected age of angioleiomyoma is between 30 to 50 decades and it is usually seen in lower leg of female. A 40-year-old female patient presented with violaceous nodule on right labium majora which appeared 4 month prior to the visit. The patient had previously visited other hospital and performed punch biopsy of the lesion. The initial histopathologic examinations revealed irregular proliferation of atypical vascular structrues in the dermis. Kaposi sarcoma was first suspected and HHV-8 immunohistochemistry was performed, but with negative result. Under the final impression of hemangioendothelioma and angiosarcoma, patient was refered for further evaluation. Secondary pathology report performed by our hospital could only suggested vascular tumor and total excision of the lesion was recommended. The patient thereafter underwent excisional surgery, and final pathologic report was consistent with angioleiomyoma. There are numerous reports of angioleiomyoma of skin arising in various parts of body, such as ear helix, upper lip, and finger. However, aside from a single study reporting angioleiomyoma of vulva, there is no previous report of the disease in labia majora. Herein we report a rare case of angioleiomyoma arising in labia majora.
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