The purpose of this study is to propose changes that can be made to improve nurse uniforms in terms of outfit and functionality based on actual wearing conditions and nurse’s preference. The proposed nurse uniform was composed of a blouse and pants. The design was as follows: the blouse had short set-in sleeve with China collar, a princess line, and it came down to middle hip. Armhole action pleats and back inverted pleats were embedded for convenient arm movements. The pants waist had a rubber band at the back waist, and the crotch length and the knee width were increased for activity. To make the pocket more accommodative, separate pocket slots treated with silicone were added to prevent belongings from coming out of the pocket. The pink tone of the uniforms, as well as the stripes on the blouses and spandex incorporated pants were based on nurses’ preference. the nurse uniforms were produced after measuring the size of women in the age of 25 to 29, and the uniform patterns were corrected after two wearing experiments. Wearing test was examined in terms of appearance and functionality. For appearance, experts gave the uniforms a mean rating of 4.30, and nurses gave a mean rating of 4.00. Functionality was evaluated in terms of ease of activity and storage aspects. The total mean of ease of activity in nursing service was 4.30, whereas the evaluation of storage in terms of pocket position and convenience was 3.80.