Background: Vitiligo remains a major challenge in dermatology. However, much of the treatment remains unclear, because little evidence is available.
Objectives: To answer some critical questions pertaining to management of vitiligo patients.
Methods: A modified Delphi process among 31 vitiligo experts was conducted. A total of 12 clinical vitiligo treatment questions without clear answers were collected via a vote. To address each question, two members performed systematic literature reviews and prepared draft statements along with the levels of evidence and strength of recommendation. After reviewing the draft, all expressed their extent of agreement from 1 (strong disagreement) to 9 (strong agreement) for each item. The drafts were revised to reflect suggested comments. Voting continued until the agreement rate did not change.
Results: The consensus process was completed after five rounds. We identified the best answers to 12 key questions, including issues on long-term phototherapy, systemic and topical corticosteroids, topical calcineurin inhibitors, immunosuppressants, excimer laser treatment, and surgical interventions.
Conclusion: This consensus would complement current guidelines and aid both physician and patient decisionmaking in the treatment of vitiligo.