Background: Skin graft for vitiligo is widely accepted as the last treatment option for patient who fails to respond to medical therapy.
Objectives: This study aimed to assess the repigmentation rate as well as to find a possible predictive factors for successful skin grafts in stable vitiligo patients.
Methods: Patients who had undergone either suction blister skin graft or mini-punch graft from October 2009 to June 2020 were restrospectively reviewed. Patient demographics and clinical characteristics were obtained. Repigmentation was assessed on the first visit after 3 months postoperative.
Results: Total 186 stable vitiligo patients had undergone 249 skin graft procedures. As for vitiligo subtype, 91(48.9%) had segmental vitiligo and 95(51.1%) had non-segmental vitiligo. Face and neck (64.8%) were the most common recipient site followed by trunk (24.7%) and extremities (10.5%). Regarding the methods of skin graft, suction blister epidermal grafting was performed in 84.7% and punch graft was done in 15.3%. After skin graft, phototherapy was added in 95.2% for prompt repigmentation. Mean duration between skin graft and the onset of repigmentation was 4.1 weeks. At 3 months postoperatively, 83.9% showed more than 75% repigmentation.
Conclusion: Skin graft is very useful treatment for stable vitiligo, however the degree of repigmentation after skin grafting could be variable depending on clinical characteristics such as vitiligo subtype and its location.